Ibuprofen Does Not Aggravate COVID-19
June 30, 2020
The Jerusalem Post — New research from BGU finds that ibuprofen does not aggravate symptoms caused by the coronavirus. This comes after the reigning controversy that rose after the French government claimed in March that ibuprofen could aggravate infections.
Following the announcement made in France, BGU researchers did a follow up study that aimed to evaluate whether the use of ibuprofen in coronavirus patients was associated with more severe cases compared with patients who used paracetamol, also known as acetaminophen, a substance that reduces fever.
Ibuprofen, an antipyretic, is also an anti-inflammatory drug, and is used as a pain killer. While paracetamol is used in treatment for similar symptoms, both drugs are metabolized in the body differently. Ibuprofen is primarily metabolized in the kidneys and paracetamol is processed in the liver.
The study was published in the Clinical Microbiology and Infection journal. It monitored the use of these medications in 403 patients in Israel, from a week before their diagnosis throughout the infection period.
Results found that there was a similar outcome between patients who took ibuprofen versus patients who took paracetamol. In fact, it was found that the rate of patients who needed respiratory support was higher in the paracetamol group with borderline significance.