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Algae Strain Identified to Reduce Cholesterol, Blood Pressure and Inflammation

Algae Strain Identified to Reduce Cholesterol, Blood Pressure and Inflammation

May 4, 2010

Medical Research, Natural Sciences, Press Releases

BEER-SHEVA, ISRAEL, May 3, 2010 – Ben-Gurion University of the Negev (BGU) researchers have isolated a microalgal strain which produces large amounts of a polyunsaturated fatty acid that could reduce blood pressure, chronic inflammation and blood cholesterol level, reducing the risk for heart attacks.

A research team at BGU’s Landau Family Microalgal Biotechnology Lab in the Jacob Blaustein Institutes for Desert Research (BIDR) headed by Prof. Zvi HaCohen, is studying an algal mutant that is capable of accumulating up to 15 percent (of dry weight) of  a polyunsaturated fatty acid (PUFA) called DGLA (Dihomo-γ-Linolenic Acid).  The new strain, IKG-1, is a freshwater microalga that the researchers believe is the only known plant source capable of producing such significant amounts of DGLA. 

“Omega-6 PUFA are necessary as components of brain cell membranes and have various nutritional uses,” explains HaCohen, incumbent of the Maks and Rochelle Etingin Chair in Desert Research and rector-elect at BGU.  

“DGLA is one of these PUFA, but appears in nature only as an intermediate in the biosynthesis of other compounds and does not accumulate to any appreciable concentration. There is no natural source for DGLA and although its beneficial effects are well known, very few clinical studies have been conducted.”

The research team also included the director of the Landau Laboratory, Prof. Sammy Boussiba; director of the BIDR Prof. Avigad Vonshak; Dr. Inna Khozin-Goldberg; and Ph.D. student Pushkar Shrestha.

 “The significant discovery of the IKG-1 microalgal mutant and its high content of DGLA could impact treatment of life-threatening diseases, such as chronic inflammations, multiple sclerosis and arteriosclerosis,” explains Dr. Ora Horovitz, vice president of business development for BGN Technologies, the technology transfer and commercialization subsidiary of BGU. 

“Our Microalgal Biotechnology Laboratory continues to be a leading innovator in its work on microalgae and its products harnessing Negev resources, such as brackish water and highly abundant sunlight. BGU is continuing to develop valuable pharmaceuticals and nutraceuticals, as well as biofuels and other potential alternative energy sources.”   

ABOUT AMERICANS FOR BEN-GURION UNIVERSITY

By supporting a world-class academic institution that not only nurtures the Negev, but also shares its expertise locally and globally, Americans for Ben-Gurion University engages a community of Americans who are committed to improving the world. David Ben-Gurion envisioned that Israel’s future would be forged in the Negev. The cutting-edge research carried out at Ben-Gurion University drives that vision by sustaining a desert Silicon Valley, with the “Stanford of the Negev” at its center. The Americans for Ben-Gurion University movement supports a 21st century unifying vision for Israel by rallying around BGU’s remarkable work and role as an apolitical beacon of light in the Negev desert.

About Ben-Gurion University of the Negev

Ben-Gurion University of the Negev embraces the endless potential we have as individuals and as a commonality to adapt and to thrive in changing environments. Inspired by our location in the desert, we aim to discover, to create, and to develop solutions to dynamic challenges, to pose questions that have yet to be asked, and to push beyond the boundaries of the commonly accepted and possible.

We are proud to be a central force for inclusion, diversity and innovation in Israel, and we strive to extend the Negev’s potential and our entrepreneurial spirit throughout the world. For example, the multi-disciplinary School for Sustainability and Climate Change at BGU leverages over 50 years of expertise on living and thriving in the desert into scalable solutions for people everywhere.

BGU at a glance:  

20,000 students | 800 senior faculty | 3 campuses | 6 faculties: humanities & social sciences, health sciences, engineering sciences, natural sciences, business & management, and desert research.

 

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James Fattal, J Cubed Communications

516.289.1496

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