BGU researchers are on the verge of a breakthrough that is bringing the world closer to a cure for diabetes.

Researchers at BGU’s Clinical Islet Laboratory are pursuing three major goals: transplants and new drugs, gene therapy, and the creation of a “transgenic” mouse that can tolerate human material for experimentation. They’re working on new drugs based on the alpha-1-antitrypsin (AAT) protein that reduces inflammation. Recent clinical trials demonstrated that infusion of AAT in recently diagnosed type 1 diabetes patients could eventually eliminate the need for insulin injections. A new clinical trial is under way to evaluate AAT dosing levels and duration.

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